Realistic model of mouse hippocampus uncovers new mechanism for pattern separation

Our brains can distinguish highly similar patterns, thanks to a process called pattern separation. How exactly our brains separate patterns is, however, not full,y understood yet. Using a full-scale computer model of the dentate gyrus, a brain region involved in pattern separation, researchers found that inhibitory neurons activated by one pattern suppress all their neighboring neurons, thereby switching off 'competing' similar patterns.

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