Research shows B cells can help fight infection, speed skin wound healing, and protect brain after injury

Until recently, B cells—present in the blood stream—were mainly thought to produce antibodies and present antigens to help with the immune response to pathogens. A research team at the Vaccine and Immunotherapy Center (VIC) at Massachusetts General Hospital (MGH) led by Ruxandra Sîrbulescu Ph.D., and Mark Poznansky, MD, Ph.D., is exploring the novel protective roles that B cells may play in the context of injury. The group previously observed that mature B cells purified from the blood or spleen can greatly accelerate wound healing in the skin and even protect the brain after injury in mice.

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