Study rewrites dogma of adenovirus infection and double-stranded RNA

Challenging the dogma of what scientists thought they understood about DNA viruses, a team of researchers led by Children's Hospital of Philadelphia (CHOP) has shown that adenovirus uses its own efficient RNA splicing mechanisms to prevent the formation of double-stranded RNA, which otherwise would trigger a host immune response. By splicing its RNA transcripts in a way that prevents them from pairing with other viral messages, adenovirus evades host sensors that activate the immune system in the presence of double-stranded RNA. The findings were published today as a "Breakthrough Article" in Nucleic Acids Research.

from Phys.org - latest science and technology news stories https://ift.tt/3AXyt7S

Comments

Post a Comment

Popular posts from this blog

Seismic study reveals key reason why Patagonia is rising as glaciers melt

The icefields that stretch for hundreds of miles atop the Andes mountain range in Chile and Argentina are melting at some of the fastest rates on the planet. The ground that was beneath this ice is also shifting and rising as these glaciers disappear. Geologists have discovered a link between recent ice mass loss, rapid rock uplift and a gap between tectonic plates that underlie Patagonia. from Phys.org - latest science and technology news stories https://ift.tt/j1h2ds5
Read more

New method to detect and visualize sperm cells recovered from forensic evidence

One of the most valuable forms of forensic evidence in cases of male-perpetrated sexual assault is the presence of semen, either in the form of stains left behind on items or on swabs collected from victims after an offense. To confirm that semen is present, suspected stains are examined under a microscope to see if any sperm cells are visible. from Phys.org - latest science and technology news stories https://ift.tt/2XBwacB
Read more