Dual action: RNA binding protein also binds DNA and acts as a damage sensor across the genome

Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome alterations during cell division. DNA mutations can arise from exposure to ultraviolet or X-ray radiation or from certain chemicals known as carcinogens; however, our cells have developed mechanisms to monitor and repair damaged DNA.

from Phys.org - latest science and technology news stories https://ift.tt/3kHC1q9

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