How can researchers quickly access complex molecules for drug discovery?

The function of molecules used in drugs in part depends on their structure, including the many chemical bonds between their atoms. These molecules can be built through several different chemical reactions, most of which are slow and inefficient because they rely on the formation of one chemical bond at a time. Ramesh Giri, Weinreb Early Career Professor of Chemistry at Penn State, has developed a reaction that creates two carbon bonds at a time across atoms in a configuration called an alkene with the help of small amounts of nickel, a sustainable and abundant catalyst.

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