Researchers decode the structure of the molecular complex that carries detoxifying enzymes in cells to the right place

Peroxisomes are essential, membrane-enclosed vesicles that occur in every cell. An arsenal of enzymes inside them breaks down harmful substances, thereby detoxifying the cells. A team of scientists led by Prof. Dr. Bettina Warscheid from the University of Freiburg, Prof. Dr. Ralf Erdmann from the Ruhr University Bochum and Prof. Dr. Christos Gatsogiannis from the University of Münster has studied the molecular complex that carries the enzymes to where they are needed in the peroxisome. They have been able to cast light on the structure of the complex with great precision and obtain insights into the mechanisms of how it functions. Their results have been published in the journal Proceedings of the National Academy of Sciences.

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