TP53 gene variant in people of African descent linked to iron overload, may improve malaria response

A rare, African-specific variant of the TP53 gene called P47S causes iron accumulation in macrophages and other cell types and is associated with poorer response to bacterial infections, along with markers of iron overload in African Americans. Macrophage iron accumulation disrupts their function, resulting in more severe bacterial infections.

from Latest Science News -- ScienceDaily https://ift.tt/2TY2cMc

Comments

Post a Comment

Popular posts from this blog

Seismic study reveals key reason why Patagonia is rising as glaciers melt

The icefields that stretch for hundreds of miles atop the Andes mountain range in Chile and Argentina are melting at some of the fastest rates on the planet. The ground that was beneath this ice is also shifting and rising as these glaciers disappear. Geologists have discovered a link between recent ice mass loss, rapid rock uplift and a gap between tectonic plates that underlie Patagonia. from Phys.org - latest science and technology news stories https://ift.tt/j1h2ds5
Read more

New method to detect and visualize sperm cells recovered from forensic evidence

One of the most valuable forms of forensic evidence in cases of male-perpetrated sexual assault is the presence of semen, either in the form of stains left behind on items or on swabs collected from victims after an offense. To confirm that semen is present, suspected stains are examined under a microscope to see if any sperm cells are visible. from Phys.org - latest science and technology news stories https://ift.tt/2XBwacB
Read more