Mitonuclear interactions in the control of life history

Mitonuclear interactions are believed to play an important role in the so-called "life history" of Eukaryotic organisms. Unfortunately, no one has come up with any sort of general concrete theory that can predict or even describe these interactions. A recent thematic issue of Philosophical Transaction of the Royal Society comprises a series of articles that attempt the formidable task of linking mitochondrial genotype to phenotype. Of note among them is an article that uses specially crafted populations of fruit flies to explore mitonuclear interactions in life history responses to changes in an organism's environment.

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